As part of the Department of Physical and Applied Sciences, the mission of the Pre-Engineering program coincides with the entire Madonna University mission regarding career preparation, and service to others and society based on Judeo-Christian principles as advanced by the Felician Sisters. The Pre-Engineering program incorporates this mission while also making a strong commitment to liberal arts education.

Though focusing on science in particular, the sciences are taught with a global perspective, incorporating the role of Pre-Engineering applications into social, environmental, ethical and human issues.